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Dr. Christabel Cheung Published in Journal of Clinical Oncology

Assistant Professor Christabel Cheung, PhD, MSW, and colleagues have a new paper published in Journal of Clinical Oncology that explores the association between socioeconomic deprivation and cancer outcomes among patients participating in clinical trials.

Using data from patients enrolled in phase III and large phase II clinical trials for major cancers conducted by the SWOG Cancer Research Network from 1985 to 2012 (n=41,109), socioeconomic deprivation was measured by trial participants\' residential zip codes linked to the Area Deprivation Index (ADI). The authors found that compared with trial participants in the most affluent areas (ADI, 0%-20%), trial participants from areas with the highest socioeconomic deprivation (ADI, 80%-100%) had worse overall (hazard ratio [HR] = 1.28, 95% CI, 1.20 to 1.37, P < .001), progression-free (HR = 1.20, 95% CI, 1.13 to 1.28, P < .001), and cancer-specific survival (HR = 1.27, 95% CI, 1.18 to 1.37, P < .001).


Unger, J.M., Moseley, A., Cheung, C.K., Ramsey, S.D., Osarogiagbon, R.U., Symington, B., Hershman, D.L. (2021) “Persistent disparities: Socioeconomic deprivation and cancer outcomes in patients treated in clinical trials.” Journal of Clinical Oncology.



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